Eicosanoids: From Biotechnology to Therapeutic Applications

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Di Bartolo, B. The apolipoprotein A-I mimetic peptide ETC exhibits anti-inflammatory properties that are comparable to high density lipoproteins. The apolipoprotein A-I mimetic peptide, ETC, reduces chronic vascular inflammation in the rabbit.

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Lipids Health Dis. Doti, N. Drucker, D. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes.

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Lancet , — Eng, J. Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas. Fabbrizzi, P. Use of click-chemistry in the development of peptidomimetic enzyme inhibitors.

Fisher, E. High-density lipoprotein function, dysfunction, and reverse cholesterol transport. Flowers, L. Characterization of a peptide inhibitor of Janus kinase 2 that mimics suppressor of cytokine signaling 1 function.

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Fosgerau, K. Peptide therapeutics: current status and future directions. Drug Discov. Today 20, — Fuster, V. Atherothrombosis and high-risk plaque: part I: evolving concepts. Gao, M. Targeting protein-protein interfaces using macrocyclic peptides. Biopolymers , — Garber, D. Turnover of synthetic class A amphipathic peptide analogues of exchangeable apolipoproteins in rats. Correlation with physical properties.

Gaudreault, N. ApoE suppresses atherosclerosis by reducing lipid accumulation in circulating monocytes and the expression of inflammatory molecules on monocytes and vascular endothelium. Gentilucci, L. Peptides and peptidomimetics in medicine, surgery and biotechnology. Getting, S. Inhibition of neutrophil and monocyte recruitment by endogenous and exogenous lipocortin 1. Global Peptide Therapeutics Market Goodwin, D. Peptides as therapeutics with enhanced bioactivity. Gordon, S. Trends Endocrinol. A comparison of the mouse and human lipoproteome: suitability of the mouse model for studies of human lipoproteins.

Proteome Res. Gupta, H. Apolipoprotein E mimetic Peptide dramatically lowers plasma cholesterol and restores endothelial function in watanabe heritable hyperlipidemic rabbits. Hatters, D. Apolipoprotein E structure: insights into function. Trends Biochem. Hecht, I. A novel peptide agonist of formyl-peptide receptor-like 1 ALX displays anti-inflammatory and cardioprotective effects. Iqbal, A. Acute exposure to apolipoprotein A1 inhibits macrophage chemotaxis in vitro and monocyte recruitment in vivo. Elife 5:e Irwin, N. New perspectives on exploitation of incretin peptides for the treatment of diabetes and related disorders.

World J. Diabetes 6, — Iwata, A. Jimenez-Solem, E. Dulaglutide, a long-acting GLP-1 analog fused with an Fc antibody fragment for the potential treatment of type 2 diabetes. Juhl, C. Bedtime administration of NN, a long-acting GLP-1 derivative, substantially reduces fasting and postprandial glycemia in type 2 diabetes. Kalra, S.

Glucagon-like peptide-1 receptor agonists in the treatment of type 2 diabetes: past, present, and future. Indian J. Kaspar, A. Future directions for peptide therapeutics development.

Toward two decades of plant biotechnology: successes, failures, and prospects

Today 18, — La, M. Annexin 1 peptides protect against experimental myocardial ischemia-reperfusion: analysis of their mechanism of action. Lawrence, T. Anti-inflammatory lipid mediators and insights into the resolution of inflammation. Lax, R. Challenges for therapeutic peptides part 1: on the inside, looking out. LeBert, D. Inflammation and wound repair.


Leening, M. Should we reconsider the role of age in treatment allocation for primary prevention of cardiovascular disease? Heart J. Li, X. Differential effects of apolipoprotein A-I-mimetic peptide on evolving and established atherosclerosis in apolipoprotein E-null mice. Liang, X.